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Preclinical studies, small controlled trials, and observational research further suggest that GLP-1 receptor agonists may have beneficial effects in the prevention and treatment of mood disorders and in psychopathology domains that substantially impair quality of life, including cognitive dysfunction and anhedonia

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However, the study had no control group and several methodological issues, so the results should be viewed with caution

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Fecal concentrations of compounds like isopropanol, p-cresol (103), and various short-chain fatty acids (106) have been demonstrated to be altered in patients with ASD