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Smith, W

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CellChat analysis showed stronger intercellular communication in the high-score group, especially involving fibroblasts, myeloid cells, endothelial cells, and epithelial cells

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Retatrutide: Complication Focus TRIUMPH-4: Obesity + knee osteoarthritis (445 participants) TRIUMPH-2: Obesity + type 2 diabetes TRIUMPH-6: Weight maintenance trial Advantage: Multiple complication-specific trials could lead to broader label (obesity + OA + OSA indications)