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Semaglutide with pyridoxine and metformin Metformin is one of the most commonly co-prescribed medications with GLP-1 agonists, particularly for patients with type 2 diabetes or insulin resistance

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Curiously, ingestion of 200 mL of pure water increases late phase plasma GLP-1, while GIP secretion is unchanged (Herrmann et al., 1995), suggesting a GIP-independent and potentially mechanically-mediated increase in GLP-1