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Novo Nordisk filed the New Drug Application (NDA) for CagriSema in early 2026, based on positive results from the REDEFINE phase 3 trial program
454 By reducing MMP expression, GLP-1R stimulation may help preserve the integrity of fibrous caps and mitigate the risk of plaque rupture
Data from small studies suggest preconception GLP-1 use may help improve pregnancy odds in this patient population
Tirzepatide is most effective when combined with healthy eating, regular physical activity, and ongoing support
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