10.1038/nmeth.2309 25 GolizehM.LeBlancA.SlenoL
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Lowers aromatase (enzyme that converts testosterone to estrogen) in ovaries
These non-incretin metabolic peptides frequently exert effects on peripheral tissues such as skeletal muscle, adipose tissue, liver, and vasculature, and often engage receptors distinct from those targeted by current therapies
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2.1.3 Calcium dysregulation and excitatory neurotransmission METH enhances glutamate release, leading to NMDAR overactivation and increased calcium influx into neurons (Staszewski and Yamamoto, 2006)