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Interestingly, interventions that boost NAD + levels resulted in extended lifespan in worms and mice 108,109,111,247 , suggesting a therapeutic potential for raising NAD + in various pathological conditions or age-associated diseases

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Estudios en animales y humanos demuestran, principalmente, una clara asociacin entre la exposicin a estos metales y la presencia de dao renal crnico, donde la fisiopatologia de cada uno de ellos es importante para entender el mecanismo de dao renal