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Some prefer GHK-Cu at a separate time of day (before bed for collagen/sleep synergy), but there's no chemical reason it can't be combined

ClinicalTrials.gov TRIUMPH-1: A Master Protocol to Investigate the Efficacy and Safety of Retatrutide (LY3437943) Once Weekly in Participants Without Type 2 Diabetes Who Have Obesity or Overweight (NCT05929066)

Patients were instructed to use high dose vitamin B12 nasal drops (5,000 mcg one nasal drop in each nostril, twice per week)

This approach ensures the oral Wegovy dosing is optimal for absorption

Unlike some medications where morning versus evening makes a pharmacological difference, weekly semaglutide injections are flexible