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Hyperinsulinemia can interfere with the signaling of GnRH, resulting in higher levels of LH and more frequent and intense GnRH pulses [57]

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The rats were fed in the standard SPF environment, housed at a temperature of 23C and in a 12h light-dark cycle

CRISPR-Cas9-mediated genome editing has successfully generated Brassica varieties with significantly increased glucoraphanin accumulation by modulating key genes in the pathway, including MYB28, AOP2, and BCAT4 (96, 107)