Although these methods have demonstrated encouraging results in small-scale studies involving MS patients and EAE models, the absence of large-scale prospective randomized controlled trials means that these findings still suffer from limited reproducibility and challenges in generalizability across diverse populations
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Hence, the effects of GLP-1 RA on the central nervous system may contribute to the induction of weight loss but not necessarily to its maintenance
Monitoring of glutathione levels may be necessary to adjust dosing appropriately
