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More than 3,000 product liability lawsuits are pending, largely focused on gastroparesis and vision injuries such as non-arteritic anterior ischemic optic neuropathy (NAION), now centralized in two MDLs in the Eastern District of Pennsylvania before Judge Karen Marston

Se supplementation is necessary in Se-deficient individuals, but may have some health risks in Se-excessive individuals, including diabetogenic effect

The warning is specific

The mechanistic rationale is strong, the safety profile is established, and the observation that psoriatic arthritis patients have lower thymosin alpha-1 levels is suggestive

Effects of GCK, GCKR, G6PC2 and MTNR1B variants on glucose metabolism and insulin secretion