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GLP-1, or glucagon-like peptide-1, is a hormone that plays a significant role in managing appetite and glucose metabolism

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For individuals with pre-existing gastrointestinal conditions such as inflammatory bowel disease, previous bowel surgery, or chronic constipation, closer monitoring may be warranted when initiating therapy

The return to an approved-only supply model is undoubtedly a win for safetybut it also reopens an uncomfortable conversation around cost

Tirzepatide provides a well-characterized, extensively documented platform for studying dual incretin agonism

Potential Demand for GLP-1s According to the Centers for Disease Control (CDC), in 2021, 29.4 million adults in the United States were diagnosed with diabetes (90 to 95 percent were T2D)