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This variabilitynot just low hormone levelsis what drives many symptoms

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Lessons from Bariatric Surgery The experience following bariatric surgery provides a strong parallel

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3) Suppresses postprandial glucagon secretion post-meal hyperglycemia

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For example, palmitoylethanolamide (PEA) is found naturally in the body, as well as in foods like egg yolk and peanuts, and is suggested to have anti-inflammatory properties

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As such, TGR5 activation stimulates secretion of GLP-1, while FXR activation reduces GLP-1 secretion, demonstrating a complex interplay between the differential bile acid pool composition and gutbrain signaling 270,271

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