Ocular manifestations of pigmentary disorders
For some local diseases related to the skin or nervous system, such as skin nerve injury, local neuropathy, etc., cream formulations can directly deliver drugs to the affected area, increase the concentration of drugs locally, and enhance the therapeutic effect
Heres an interesting fact: Nimesulides unique mechanism targets only the COX-2 inflammatory pathway, reducing GI side effects but increasing the risk of liver toxicity, which is rarely discussed in typical medical conversations
Available from: Olsen CM, Pandeya N, Green AC, Ragaini BS, Venn AJ, Whiteman DC
However, its important that if you have a personal history or first degree relative with a history of c-cell thyroid tumor or multiple endocrine neoplasia, type two that you discuss this with your provider as these may not be a good medication choice for you
Gonzalez-Mariscal L, Betanzos A, Nava P, Jaramillo BE