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The concern isnt just that youll develop antibodies against the peptide itselfits that those antibodies might cross-react with your own endogenous proteins

Tumor targeting peptides: novel therapeutic strategies in glioblastoma

Interestingly, Hmox-1 RNA levels, not increased at 6 h like in WT mice, were progressively augmented later and may have a protective role during liver regeneration by modulating MnSOD and catalase expression

They are different molecules with different mechanisms, different efficacy profiles, and different regulatory statuses

Stack two that work on different systems and you cover more ground without piling on side effects from the same receptor getting hit twice

However, it is important to note that neurological symptoms can occur even in the absence of anaemia, particularly in patients taking folic acid supplements, which can mask the blood changes whilst neurological damage progresses