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They dont have to have tests or clinical trials or whatever to show they work, but they cant be harmful, and they cant make disease claims. CNNs John Bonifield contributed to this report.

Key studies to be aware of: Pickart et al

Vitamin B12 is not considered dangerous for most men, but excessive supplementation may mask underlying health issues, such as folate deficiency, if not managed with proper medical supervision

Certain Bulk Drug Substances for Use in Compounding May Present Significant Safety Risks

Healthcare professionals often prefer injections for localized treatment or when IV access is difficult

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