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Ethacraplatin a dual-threat platinum (IV) prodrug is a cisplatin molecule coordinated to two ethacrynic acid ligands which is able to inhibit irreversibly GSTP1-1 enzymatic activity being reduced and cleaved as a consequence of binding (Fig
Awad, A
[DOI] [PubMed] [Google Scholar] 13.Sikiric P., Seiwerth S., Rucman R., Turkovic B., Rokotov D.S., Brcic L., Sever M., Klicek R., Radic B., Drmic D., et al
Model System Selection: Choose experimental systems that allow meaningful comparison of stability and activity differences
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Ophthalmology 121 , 979987 (2014)
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