By comparison, orlistat (Xenical) produced approximately 3-4 kg more weight loss than placebo over 12 weeks in its pivotal trials, and GLP-1 agonists produce 8-15 kg more than placebo
PubMed, Kim, Tae-Ho, et al
Even with a calculator, take a moment to confirm the numbers
Remember Mike and James are coming to the UK to present in two seminars one in Brighton (18th May) and one in London (21st and 22nd May)
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The screening identified quinoliniums as a promising scaffold, and 5-Amino-1MQ emerged as one of the most active compounds with an IC 50 of approximately 1.2 M under the biochemical assay conditions used