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Some researchers suggest metabolic shifts as the body adjusts to altered fat metabolism could trigger them

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Moreover, given that AD has been described as type 3 diabetes, with evidence suggesting peripheral metabolic dysfunction may play a role in disease initiation and progression (similar to the peripheral-to-central spread proposed in Parkinsons disease), blood transcriptomic analysis offers a relevant and practical window into the early disease mechanisms we sought to evaluate

This highlights the uniqueness of human thyroid and the importance of Se to the thyroid gland