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Dose-related effects of GLP-1 on insulin secretion, insulin sensitivity, and glucose effectiveness in mice

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Amylin acts on amylin receptors in the brainstem to reduce food intake and improve glucose metabolism by delaying gastric emptying and inhibiting glucagon secretion

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the study's lead author and a professor of radiology in the University of Pennsylvania Perelman School of Medicine, said in a statement that the findings were "observational" and do not "definitively confirm an association between GLP-1 medications and reduced breast cancer incidence," however the study "does add to the growing body of evidence suggesting that it's worth investigating these weight-loss drugs as potential cancer prevention tools." Narula reiterated that the new study is "hypothesis-generating" not "practice-changing," though the study does add to a growing body of similar research