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According to FDA, GLP-1RA had not shown evident risk of pancreatitis and pancreatic tumor (111)

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While the exact mechanisms remain unclear, several factors are implicated, including nutritional aspects, mechanical unloading, loss of lean mass, and alterations in the secretion of gut hormones and adipokines [8, 10]

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Analysts at JP Morgan recently doubled their predictions for the incretin class to $71 billion within the next 10 years