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A similar trial also showed faster angiogenesis with a week of injections in lab animals

Last updated: March 9, 2026 If you are considering B12 injections this spring whether as part of a pre-summer wellness refresh or to address persistent fatigue understanding the risks is just as important as knowing the benefits

When compared to patients with low MMA and low B12 (MMA low B12 low ), the multivariate-adjusted HRs (95% CIs) for total mortality in the MMA low B12 high, MMA high B12 low , and MMA high B12 high groups were 0.90 (0.731.12), 1.27 (0.951.69), and 1.98 (1.462.69), respectively

Contact your GP if you experience persistent or worsening sleep problems that coincide with starting B12 supplements, particularly if accompanied by other symptoms