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Abstract Glucagon like peptide-1 (GLP-1), a peptide hormone from the intestinal tract, plays a central role in the coordination of postprandial glucose homeostasis through actions on insulin secretion, food intake and gut motility

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FOXO4-DRI represents a peptide-based senolytic approach that is more targeted than small-molecule senolytics like dasatinib plus quercetin, which affect broader cellular pathways

After informed discussion of risks, benefits, and cost, patient preference is a valid reason

The opportunity for preservation has passednow youre managing disease rather than preventing it