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Description

But that sweet tooth shift has left a bitter aftertaste

It's like the difference between sipping water through a straw versus jumping into a refreshing pool

Specific event rates included nausea (55% vs 12.6%), constipation (30.7% vs 11.6%), and vomiting (26.1% vs 4.1%)

10.1073/pnas.051551698 355

This setback reflects broader challenges associated with therapies targeting the amyloid-beta pathway, which has dominated Alzheimers research for decades

However, it ended clinical trials in June 2023 for its second obesity and Type 2 diabetes mellitus treatment, lotiglipron