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Increased interest in functional foods reflects consumers evolving preferences towards health and well-being, rather than only obtaining dietary nutrition [5]

The ferroptosis pathways within nerve cells include iron homeostasis regulation, cystine/glutamate (Glu) reverse transporter (system xc ), glutathione (GSH)/glutathione peroxidase 4 (GPX4), and lipid peroxidation

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The study has demonstrated a higher serum level of IL-15 in vitiligo patients than in controls, highly associated with epidermal H 2 O 2 content and the disease activity (82, 83)

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10.1016/j.molmet.2022.101647 27 GulottaL