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[1] [3] More serious but rare risks include pancreatitis, diabetic retinopathy complications (particularly in people with pre-existing retinopathy and rapid improvement in glycaemic control), gallbladder disease (cholelithiasis/cholecystitis), and potential thyroid C-cell tumours (observed in animal studies)

Additionally, as more patients with LAL-D survive into adulthood thanks to the enzyme replacement therapy, the transition from pediatric to adult care has emerged as an important challenge

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Association of body mass index with lifetime risk of cardiovascular disease and compression of morbidity

Transl Neurodegener 15 , 5 (2026)

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