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This is the first clinical trial of semaglutide for MASLD in people with HIV

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This beneficial effect is, at least in part, due to the activation of the MET-AKT/GSK-3 signaling pathway (Jia et al., 2020)

Medical Guidance: Who Should Consider Duration When Dosing Patients with significant renal impairment, hepatic disease, advanced age, or those taking medications that inhibit GLP-1 metabolism should discuss duration implications with their provider before starting therapy

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