Microorganisms 9 , 2376 (2021)
Central Nervous System Agents in Medicinal Chemistry
I know this was posted a while back and dont know your progress since then
The WHO estimates it affects between 1020% of people infected with SARS-CoV-2 tens of millions globally.1 The symptoms are wide-ranging but cluster into recognizable patterns: Neurological: brain fog, cognitive impairment, headaches, sleep disruption Cardiovascular: chest pain, breathlessness, tachycardia (POTS), reduced exercise tolerance Immune: persistent low-grade inflammation, recurrent infections, autoimmune flares Musculoskeletal: post-exertional malaise (PEM), joint pain, muscle weakness Metabolic/endocrine: insulin dysregulation, thyroid disruption, adrenal fatigue signals Standard care rest, symptom management, antidepressants, rehabilitation programs helps some patients
The concentration of GABA decreased from 926.36 0.12 g/mg
It is also indicated that hyperthermia stimulated the heat-inducing factor I (HIF-I), and its downstream molecules of vascular endothelial growth factor (VEGF) and pyruvate dehydrogenase kinase I (PDK I) leading to enhanced perfusion and oxygenation
