Lovorka Batelja Vuletic, Departments of Pharmacology and Pathology, Medical Faculty University of Zagreb, Zagreb 10000, Croatia
Thiazide Diuretics
Light, refreshing, and completely gluten-free
Exosome formation increased after GPX4 inhibition, which contained prominin and TSG101, as well as ferritin, while blocking the export of exosomes resulted in the accumulation of iron, indicating that in the state of cellular oxidative stress, prominin 2 can promote the formation of iron-containing exosomes and transport intracellular iron to the extracellular space, thereby enhancing cell resistance to ferroptosis [75]
Optimizing drug exposure to minimize selection of antibiotic resistance
Nanoparticles responsive to GSH are capable of delivering both chemotherapeutic drugs and inhibitors, such as an oxaliplatin-based prodrug combined with an IDO-1 inhibitor (indoleamine 2,3-dioxygenase 1)