A licensed medicinal product and also a non-medicinal product
What are the benefits of vitamin B12
Additionally, patients using both treatments may attribute weight loss or adverse effects to the wrong agent, complicating clinical assessment
Additionally, electrophysiological experiments have shown the direct effects of B vitamins on pain transmission pathways in the spinal cord and thalamus, which explains the observed reduction or loss of pain sensation in clinical patients
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The complex travels through the small intestine until it reaches the terminal ileum, where specialised receptors called cubam (a complex of cubilin and amnionless proteins) recognise and facilitate the uptake of the B12-IF complex into enterocytes (intestinal cells)