Mild nausea and reduced appetite are expected with GLP-1 therapy, but severe vomiting, signs of dehydration (dizziness, dark urine), significant mood changes, or inability to eat enough calories warrant immediate contact with your provider
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Factor #2: PCOS improvement happens faster than expected For women with PCOS, GLP-1s create a perfect storm of fertility improvement through improved insulin sensitivity (which is often the root problem in PCOS), reduced androgen levels as testosterone and other androgens drop when insulin improves, ongoing weight loss effects where each pound lost further improves hormonal balance, and potentially direct ovarian effects as some evidence suggests GLP-1s may directly improve ovarian function
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