It also delivers prebiotic fiber that feeds the microbiome through slow fermentation to support colonization of skinny gut bacteria Akkermansia and Bifidobacterium
Zangabad PS, Vasani RB, Tong Z, Anderson D, Rudd D, Hick CA, et al
Bivirkningerne er gastrointestinale og typisk mest udtalt i opstartsfasen: Meget hyppige (over 10% af deltagerne): Kvalme Opkastning Diarr Forstoppelse Hyppige (1-10%): Nedsat appetit Trthed Mavesmerter Srlige opmrksomhedspunkter: Puls: Retatrutide ger hvilepulsen med 3-5 slag i minuttet ved hjeste dosis, en forventet effekt af glukagonreceptoraktivering Galdeblre: Som med andre GLP-1-agonister er der get risiko for galdesten ved hurtigt vgttab Skjoldbruskkirtlen: Dyreforsg viser get risiko for C-cellehyperplasi, dette overvges tt i de kliniske studier Frafaldet pga
Under its influence, the feeling of satiety increases, gastric emptying slows down and spontaneous food intake decreases
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Results: nejm.org/doi/full/10.10 #ADA2023 Retatrutide, a TRIPLE agonist (GLP1, GIP, glucagon), just released phase 2 trial results demonstrating 25% weight loss in half of people with #obesity
