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Searches of PubMed and ClinicalTrials.gov did not identify a peer-reviewed study or registered clinical trial of the exact four-component KLOW formulation reviewed for this article

A good comparison therefore begins with the hypothesis

Proteomics 13 (10-11), 16601666

3 Studies in animal models have reported an increased requirement for cysteine in sepsis, probably due to an increased turnover of GSH, as GSH synthesis accounts for 40% of the increased cysteine utilization

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NAC may be more readily absorbed and utilized by the body than supplemental glutathione itself, as glutathione can be broken down during digestion