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Understanding these effects is essential for both patients and healthcare professionals to manage expectations and optimise treatment adherence

However, starting at 12 years of age, tHcy concentrations in plasma increased up to 92 mol/l (Fig

Rather than relying solely on willpower, these medications help regulate appetite and improve metabolic function

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10.1016/j.jnutbio.2020.108556 J Nutr Biochem

Key outcomes (surgery vs GLP-1 medicines alone) Compared to medications, surgery offers: 32% lower risk of death (all-cause mortality) 35% lower risk of major cardiovascular events (heart attack, heart failure, stroke) 47% lower risk of serious kidney disease 54% lower risk of diabetes-related eye damage (retinopathy) Greater average 10-year weight loss: ~21.6% vs ~6.8% Bigger A1c reduction: 0.86% vs 0.23% Why Surgery Outperformed GLP-1s in the Real World Adherence: Whether or not youre in a study, if you have weight loss surgery, you are left with a permanent tool to help you lose weight and maintain that loss, providing you follow some basic rules