Published studies report that KPV reduces IL-6, IL-1, and TNF- expression in macrophage and epithelial cell models, with particular documentation in gut inflammatory research [7,8]
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Vials stored at room temperature after opening may lose bacteriostatic capacity in as few as 1014 days
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It exhibited its immunomodulatory effect by decreasing the expression levels of MyD88, TLR4, TRAF6, and p65 genes and increasing the expression levels of I-B gene, MyD88, TLR4, TRAF6, phosphorylation p65, and phosphorylation I-B proteins in TLR4- NF-B signaling pathway
