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Succinyladenosine accumulation has been reported in inborn errors of metabolism that disrupt purine metabolism and mitochondrial function, such as adenylosuccinate lyase (ADSL) deficiency and fumarase deficiency [49, 50], and its consistent upregulation in MMA may reflect secondary effects on nucleotide metabolism or mitochondrial energy balance, representing an underexplored aspect of MMA pathophysiology
Dogs fed vegetarian or vegan diets are at risk of becoming cobalamin deficient
2024;19:e0313507
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A study demonstrated that curcumin upregulates this miRNA, resulting in the suppression of PI3K/Akt signalling and a subsequent reduction in the proliferation rate of A549 cells (Jin et al., 2015)
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