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A transcriptional circuit filters oscillating circadian hormonal inputs to regulate fat cell differentiation

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Specialized enteroendocrine cells in the gut lining detect luminal contents and release neuroactive hormones, while gut-associated lymphoid tissue (GALT) coordinates immune responses to microbes

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The approximate IC 50 (Inhibitory Concentration 50) concentration of 5-FU in HCT-116 cells was found to be 50 M, and this dose was chosen for the subsequent experiments (Fig