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Tirzepatide Once Weekly for the Treatment of Obesity New England Journal of Medicine 387(3) 2022PMID: 35658024 NEJM 3 Drucker DJ Mechanisms of Action and Therapeutic Application of Glucagon-like Peptide-1 Cell Metabolism 27(4) 2018PMID: 29617641 PubMed 4 Lincoff AM, Brown-Frandsen K, Colhoun HM, et al

These results were obtained because of the length of the C-H alkyl chains 58 , low hydrophilic lipophilic balance (HLB) value and the hydrophobic moiety 59 , the higher the gel-liquid phase transition temperature and low surface free energy 57 of Span 60

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