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Fungal endophytes in plants and their relationship to plant disease

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GGT-related detoxification of Pt(II) medication is a key mechanism of drug resistance (136)

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The utilization of drugs targeting key enzymes in metabolic pathways of metabolites, or enzymes involved in metabolite modifications and demodifications, or knocking out related genes at the genomic level, is considered to be able to effectively inhibit the proliferation, metastasis, and chemoresistance of tumors

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