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PMID: 27678069 Vercellini P, et al

The nootropic effect was modest (10%)

But unauthorized peptides the kind sold online, through personal trainers, or via unverified compounding pharmacies carry real risks

They reported the results in a 2020 Nature paper and published similar experiments showing the inverse Mpemba effect in PNAS earlier this year

The chemical structure is: Dihydroergotamine mesylate nasal spray is provided for intranasal administration as a clear, colorless to light yellow aqueous solution in an amber glass vial containing: Each milliliter contains (equivalent to 3.43 mg dihydroergotamine) Mechanism of Action Dihydroergotamine binds with high affinity to 5-HT1D and 5-HT1D receptors