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2012 exemplified the expected effects of delocalizing FAK from focal adhesions in cancer cells: reduced viability, induction of apoptosis, and reduced invasion
Oncogene 34 , 45704580 (2015)
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To interrogate the potential effect of the lipidation on the Cagri-bound structures, we also determined structures of the CTR and AMY 1 R bound to a Cagri analogue lacking the N-terminal lipidation (CagriBB)
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