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Dosage adjustments are necessary in patients taking potent CYP3A4 inhibitors such as ritonavir, ketoconazole, and itraconazole (see Dosage and Drug Interactions)

Compounded drugs should only be used in patients whose medical needs cannot be met by an FDA-approved drug

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Plasma hyaluronan, hyaluronidase activity and endogenous hyaluronidase inhibition in sepsis: an experimental and clinical cohort study

Beyond credit risk, patients should contact their current insurer to confirm no unauthorized claims were filed using their medication history

10.1038/ajg.2013.52 Summary Keywords melanosis coli, colonic neoplasms, colonic polyps, colectomy, case report Citation Zhao W, Chen J, Xing H, Yu J and Liu Q (2022) Case report: Melanosis coli combined with colon cancer, causality or coincidence