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Dose-response analysis revealed a similar IC 50 value (the drug concentration that inhibited 50% cell viability) in both melanocytic cell lines (A375 = 8.4M 0.2 M and SK-MEL-28 = 8.7M 0.15 M) (Figure 1)

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Histone deacetylases including SIRT1, interact with STAT3 and negatively regulate its transcriptional activity by deacetylating critical lysine residues (Nie et al., 2009)

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Such genetic alterations were all reverted by low doses if IGF-1 replacement therapy for only 10 days

This compounded formulation is not those products and is not interchangeable with them