This distinction has shown to provide substantial weight reduction and improved glycemic control in adults with obesity and type 2 diabetes
They can lose weight and keep it off as time goes by
And for a significant number of women, the side effects are intolerable or not worth it given their disappointing weight loss results
Injectable GLP-1s may be more suitable for: Patients aiming for the maximum possible reduction in body weight, those with co-existing conditions like heart disease or chronic kidney disease (due to specific FDA approvals for Ozempic), or those who prefer a simple weekly medication schedule
Subsequent meta-analyses of cardiovascular outcomes trials with GLP-1RAs have clearly excluded a causal role for GLP-1RAs in acute pancreatitis (63, 69, 70), while therapy with inhibitors of dipeptidyl peptidase-4 may lead to a minor elevation of this risk (69)
Andrikou E, Tsioufis C, Andrikou I, et al