Although there is a dearth of bioavailability data for many of the peptide nasal sprays, a study showed that direct intratracheal instillation of a lyophilized powder at high concentrations could achieve reasonable levels of systemic absorption [13]
Wu et al., 2017a
Risks When total energy intake and fat consumption are within recommended levels, limiting foods high in saturated and trans fats and increasing the intake of foods rich in unsaturated fats poses no known risks
Amjad S, Nisar S, Bhat AA, Shah AR, Frenneaux MP, Fakhro K, et al
The scientific database on BPC-157 primarily consists of preclinical studies (in vitro and animal models)
Summary: There is no official contraindication or documented pharmacological interaction between Wegovy (semaglutide) and ibuprofen, and they can generally be used together safely for short-term pain relief