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Nowadays, LY3502790 and PF-06882961 (231233), a class of oral non-peptide small molecule GLP-1RAs with preferable efficacy and anti-diabetes potential, are at the stage of pre-clinical research

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Weight regain commonly occurs when discontinuing either medication, as the underlying appetite and metabolic changes return toward baseline

The carbohydrate restriction of ketogenic diets further reduces glucose availability, potentially necessitating medication adjustments

2017;53(2):S13142

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