Helps regulate appetite and provide steady energy levels, contributing to better weight management
GLP-1 receptor activation promotes insulin secretion in response to meals, suppresses glucagon release, slows gastric emptying, and reduces appetite by acting on satiety centres in the brain
The UVA researchers concluded that GLP-1 induced weight loss comes with a cost : a significant portion of the weight lost is lean mass (muscle), and theres no clear enhancement of fitness to offset that
1 2 "Biosynthesis of lipoprotein lipase in cultured mouse adipocytes
Considering that GLP-1 infusion increases postprandial satiety in normal weight 7 as well as obese humans, 14 a delay in the postprandial GLP-1 response might affect food intake regulation and in particular impact inter-meal snacking that has been shown to be augmented after sleep loss
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