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Semaglutide administered subcutaneously lowers HbA1c more than any other long-acting medication

Tirzepatide was FDA-approved for T2D in 2022, and showed impressive weight reductions in subsequent obesity trials

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Their use for Alcohol Use Disorder (AUD) or drug addiction is considered "off-label." However, groundbreaking clinical research from 2025 and 2026 demonstrates that these medications significantly dampen the brain's reward centers, drastically curbing cravings for alcohol, opioids, and nicotine