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GLP-1 effects on the brain The GLP-1 receptor is expressed in the hypothalamus, brainstem, and other parts of the central nervous system, helping GLP-1 drugs to reduce body weight by decreasing hunger and increasing feelings of satiety

It helps reduce fat accumulation by promoting healthy digestion, reducing inflammation, and balancing blood sugar levels

Osmotic laxatives such as macrogol (polyethylene glycol) are often considered first-line for chronic constipation on GLP-1 therapy, as they draw water into the bowel to soften stools

Everyone responds differently to the medication, so while some may see quick results, for others, the changes may be slower and more gradual

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