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Drugs that block VEGF have become important cancer treatments precisely because tumors depend on this pathway for growth

2 Mechanisms of OS-induced nerve damage In the context of DN, OS contributes to oxidase activation, mitochondrial dysfunction, apoptosis, inflammation, and endoplasmic reticulum (ER) stress, which are critical in the pathogenesis of nerve injury (Figure 1)

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Formaldehyde samples of a defined concentration were used to calibrate the system