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Anna Pastore, Francesco De Peppo And Anna Alisi have contributed equally to this work Key Points Weight loss is the mainstay of treatment of obesity-related metabolic-associated fatty liver disease (MAFLD)

Inside the ileum cells, B12 binds to another protein, transcobalamin II (TCII), and enters the bloodstream

In the context of muscle metabolism, this process is essential for maintaining optimal energy output, endurance and recovery, especially during intense physical activity

Glutathione is known for its antioxidant properties that may support overall skin health and can help maintain a youthful appearance